Influenced by Robert O. Becker, Marino performed animal studies and biophysical calculations that showed electromagnetic energy from powerlines and cellphones penetrated the body and caused physiological effects.

Marino testified that uncontrolled exposure of humans to man-made electromagnetic energy in the environment was a health risk, submitted amicus briefs in opposition to arguments by the power industry that human exposure to powerline electromagnetic energy was completely safe, described the legal basis in tort for damages caused by electromagnetic energy, and provided a formal articulation of the reliability of the environmental science.

Marino characterized as involuntary human experimentation, the intentional exposure of the public by industrial stakeholders to man-made electromagnetic energy in cases where the stakeholder failed to provide unbiased laboratory evidence, prior to commencing exposure, supporting claims that the exposure would be safe.

Following government muddling of the health-risk issue, and the termination of health-independent funding of related research regarding electromagnetic energy, Marino’s research focused on the immediate cybernetic consequences of human exposure to electromagnetic energy.

In many experiments involving human volunteers, Marino and co-workers studied the effect of powerline and cellphone electromagnetic energy on the electrical activity of the brain. Each experiment was sanctioned, in advance, by appropriate authorities who reviewed the experimental design to ensure its scientific merit, verified that the exposure had no more than minimal risk, and ensured that each volunteer gave written informed consent to participate in the study. The results of the experiments proved, to a statistical certainty, that the applied electromagnetic energy altered the brain activity of almost every volunteer.

Marino proposed theories to explain the underlying physiological processes that linked energy-induced changes in brain electrical activity with the occurrence of disease.

Marino described biophysical models of processes by which free nerve endings in specialized neurons in the trigeminal nerve could overcome kT, the randomizing thermal energy in the cell membrane, thereby permitting the cell to detect the presence of powerline and cellphone energy notwithstanding kT.

He showed that probabilistic but not deterministic scientific explanations of health effects in the exposed population were possible, because the physiological consequences of man-made electromagnetic energy were nonlinear, and because human beings were far from energy equilibrium. Taken together, these conditions rendered impossible the linear, deterministic explanations demanded by industry experts, and vitiated their arguments that human exposure was completely safe.